Synthesis of hybrid 1,2,3-triazolo-δ-lactams/lactones using Huisgen [3+2] cycloaddition ‘click-chemistry’ in water

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2010-03

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Elsiever

Abstract

The synthesis of a new class of hybrid 1,2,3-triazozlo-δ-lactams/lactones has been achieved using the Huisgen [3+2] dipolar cycloaddition ‘click-chemistry’ reaction of various organic azides with an activated alkyne in water, followed by cyclization.

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Chemistry, Synthesis, Hybrid 1,2,3-triazolo-δ-lactams/lactones, Click-chemistry

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