Targeting HSP90/Survivin using a cell permeable structure based peptido-mimetic shepherdin in retinoblastoma
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Date
2016
Authors
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Journal ISSN
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Publisher
Elsiever
Abstract
Retinoblastoma (RB) is a childhood retinal malignancy. Effective therapeutic strategies are still being investigated in RB disease management. Here, the anti-cancer effect of shepherdin, a peptido-mimetic inhibiting heat shock protein (HSP90)-Survivin interaction has been analyzed.
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Keywords
Biology, Heat shock proteins, Survivin, Peptido-mimetic (shepherdin), Retinoblastoma