Compression

Abstract

Compaction of powder involves compression and consolidation of the solids on the application of pressure. The forces involved in these processes play an important role in the design and development of solid oral dosage forms including tablets, filling of the hard-gelatin capsule, and in the handling of powders. Assessment of the forces on punches, axial forces, radial forces, frictional forces, and ejection forces gives us information regarding the compaction behaviour of the powder. Several mathematical terms to describe the compaction processes are studied such as the heckle plot. Optimizing the parameters that affect these forces would produce a product of the desired quality. In this chapter, we have discussed in detail about compression, consolidation, and forces involved in compaction and their impact on the quality of the product.