Design, Synthesis and In Vitro Evaluation of 2-Oxo-N-substituted Phenyl-2H-chromene-3-carboxamide Derivatives as HIV Integrase Strand Transfer Inhibitors
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Date
2020
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Publisher
Bentham Science
Abstract
A series of eighteen 2-Oxo-N-substituted phenyl- 2H-chromene-3- carboxamide analogues has been evaluated for HIV-1 integrase (IN) inhibition.
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Keywords
Pharmacy, Acquired immune deficiency syndrome (AIDS), HIV-1 inhibition, HIV-1 integrase, Chromene-3-carboxamide, Cytotoxicity, Strand transfer inhibitors