Copper-catalyzed synthesis of quinoline derivatives via tandem Knoevenagel condensation, amination and cyclization

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dc.contributor.authorKumar, Anil
dc.contributor.authorKumar, Dalip
dc.date.accessioned2021-10-14T13:13:25Z
dc.date.available2021-10-14T13:13:25Z
dc.date.issued2016
dc.description.abstractA novel regioselective synthesis of 2-aminoquinolines and 2-arylquinoline-3-carbonitriles is described via copper-mediated tandem reaction. Formation of substituted quinolines involves Knoevenagel condensation of ortho-bromobenzaldehyde with active methylene nitriles followed by copper-catalyzed reductive amination and intramolecular cyclization.en_US
dc.identifier.urihttps://pubs.rsc.org/en/Content/ArticleLanding/RA/2016/C6RA03798D
dc.identifier.urihttp://dspace.bits-pilani.ac.in:8080/xmlui/handle/123456789/2847
dc.language.isoenen_US
dc.publisherRSCen_US
dc.subjectChemistryen_US
dc.subjectCopper-Catalyzeden_US
dc.subjectKnoevenagel condensationen_US
dc.titleCopper-catalyzed synthesis of quinoline derivatives via tandem Knoevenagel condensation, amination and cyclizationen_US
dc.typeArticleen_US

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