Apoptosis inducing activity of steroidal constituents from Solanum xanthocarpum and Asparagus racemosus

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dc.contributor.authorPaul, Atish Tulshiram
dc.date.accessioned2023-12-27T10:44:53Z
dc.date.available2023-12-27T10:44:53Z
dc.date.issued2010-08
dc.description.abstractA series of Sarsapogenin and Diosgenin derived steroidal constituents (1-12), isolated from Solanum xanthocarpum and Asparagus racemosus were screened for their ability to induce cell death and apoptosis of colon carcinoma cells. The carbohydrate moieties linked to the steroid backbones were found to strongly influence cytotoxic activity and cell death mode (apoptosis or necrosis). Compound 10, from A. racemosus was found to be a potent inducer of apoptosis.en_US
dc.identifier.urihttps://www.sciencedirect.com/science/article/pii/S0944711310000334
dc.identifier.urihttp://dspace.bits-pilani.ac.in:8080/xmlui/handle/123456789/13539
dc.language.isoenen_US
dc.publisherElsevieren_US
dc.subjectPharmacyen_US
dc.subjectAnticancer activityen_US
dc.subjectApoptosisen_US
dc.subjectSarsapogenin and Diosgenin derived steroidal constituentsen_US
dc.subjectGlycoalkaloidsen_US
dc.subjectSolanum xanthocarpumen_US
dc.subjectAsparagus racemosusen_US
dc.titleApoptosis inducing activity of steroidal constituents from Solanum xanthocarpum and Asparagus racemosusen_US
dc.typeArticleen_US

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