Sequential Copper-Catalyzed Sonogashira Coupling, Hydroamination and Palladium-Catalyzed Intramolecular Direct Arylation: Synthesis of Azepino-Fused Isoindolinones

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dc.contributor.authorKumar, Anil
dc.date.accessioned2021-10-14T13:11:25Z
dc.date.available2021-10-14T13:11:25Z
dc.date.issued2017-11-09
dc.description.abstractA modular synthesis of azepino-fused isoindolinones has been developed in form of a sequential copper- and palladium-catalyzed tandem reaction. The developed protocol involved the formation of one carbon–nitrogen and two carbon–carbon bonds in a one-pot fashion. The palladium-catalyzed intramolecular direct-arylation step involves the formation of an unusual eight-membered palladacycle.en_US
dc.identifier.urihttps://chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/ejoc.201701379
dc.identifier.urihttp://dspace.bits-pilani.ac.in:8080/xmlui/handle/123456789/2829
dc.language.isoenen_US
dc.publisherWileyen_US
dc.subjectChemistryen_US
dc.subjectCopper-Catalyzeden_US
dc.subjectSonogashira Couplingen_US
dc.subjectAzepino-Fused Isoindolinonesen_US
dc.titleSequential Copper-Catalyzed Sonogashira Coupling, Hydroamination and Palladium-Catalyzed Intramolecular Direct Arylation: Synthesis of Azepino-Fused Isoindolinonesen_US
dc.typeArticleen_US

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