The Role of TRPV1 in Acquired Diseases: Therapeutic Potential of TRPV1 Modulators

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dc.contributor.authorKhare, Pragyanshu
dc.date.accessioned2024-01-23T09:17:17Z
dc.date.available2024-01-23T09:17:17Z
dc.date.issued2015
dc.description.abstractThe transient receptor potential vanilloid 1 (TRPV1) is a nonselective cation channel with high calcium permeability that has been studied extensively since its identification and characterization in 1997. Its involvement in different modalities of pain has been well documented, which has resulted in the development of novel strategies for the treatment of pain. However, TRPV1 is also involved in a plethora of other physiological and pathophysiological functions related to urinary, cardiovascular, gastrointestinal, respiratory, and central nervous systems. Here, we summarize the recent developments of the role of TRPV1 in acquired diseases and review the current perspective of TRPV1 agonist and antagonist as potential drugs for therapeutic intervention.en_US
dc.identifier.urihttps://www.sciencedirect.com/science/article/pii/B9780124200241000035
dc.identifier.urihttps://dspace.bits-pilani.ac.in/xmlui/handle/123456789/13928
dc.language.isoenen_US
dc.publisherElsevieren_US
dc.subjectPharmacyen_US
dc.subjectTRPV1en_US
dc.subjectNociceptorsen_US
dc.subjectInflammatory mediatorsen_US
dc.subjectPainen_US
dc.subjectCGRPen_US
dc.subjectCalciumen_US
dc.titleThe Role of TRPV1 in Acquired Diseases: Therapeutic Potential of TRPV1 Modulatorsen_US
dc.typeArticleen_US

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