Department of Mechanical engineering
Permanent URI for this collectionhttp://localhost:4000/handle/123456789/1921
Browse
3 results
Search Results
Item Basic principles of impedance spectroscopy(CRC Press, 2023) Bhatt, GeetaImpedance spectroscopy of biomolecules is a growing domain that deals with the study and analysis of various analyte molecules to express high-utility applications. The analytes can be directly extracted from the environment or are derived from nature through some biological/biochemical processes. The common biological analytes are drugs, DNA/RNA, cells, pathogenic bacteria, enzymes, ions, and gases. Impedance analysis measures the impedance characteristics of an analyte over a long-range frequency sweep and interprets its behavior for various frequency domains. This detection method can be utilized for analysis in an independent or integrated format with various discrete analysis/supporting techniques. Along with extensive application in the biomedical field, this technique is also used in several other applications like the analysis of electroactive polymer thin films, colloids, lubricants, paints, and batteries/fuel cells. This chapter explains the utility of impedance analysis through a detailed explanation of fundamental principles, its several components, equivalent circuit diagrams, and their common applications.Item Impedance spectroscopy and its application in biological detection(CRC Press, 2023-12) Bhatt, GeetaThis book includes basics of impedance spectroscopy technology, substrate compatibility issues, integration capabilities, and several applications in the detection of different analytes. It helps explore the importance of this technique in biological detection, related micro/nanofabricated platforms and respective integration, biological synthesis schemes to carry out the detection, associated challenges, and related future directions. The various qualitative/quantitative findings of several modules are summarized in the form of the detailed descriptions, schematics, and tables. Features: Serves as a single source for exploring underlying fundamental principles and the various biological applications through impedance spectroscopy Includes chapters based on nonbiological applications of impedance spectroscopy and IoT-enabled impedance spectroscopy-based methods for detection Discusses derivations, substrates, applications, and several integrations Describes micro/nanofabrication of impedance-based biological sensors Reviews updated integrations like digital manufacturing and IoTItem DNA-Based Sensors(Springer, 2017-12) Bhatt, GeetaSensing and detection for clinical diagnostic can be accomplished through various routes. Additionally what and how of sensing is critically optimized to meet individual needs. Diagnostics is carried out with various types of sensors out of which the electrochemical sensors are most used due to their unique ability to couple seamlessly with electronic circuitry. The DNA sensor is one of the most common types of sensors which is majorly deployed to perform expression monitoring, transcription profiling, etc., for example, the products developed by Affymetrix and Nanogen. This chapter is a consolidated review of the various aspects of DNA sensors, like the principle of detection, various ways of sensing and detection, applications of such DNA-based sensing. It looks at the various principles that are utilized for gene mapping like dielectrophoresis, polymerase chain reaction (PCR), real-time PCR or quantitative PCR (better known as q-PCR), hybridization, solid-phase PCR, droplet-based PCR, etc. It also reviews various sensing/detection strategies for sensing DNA like electrophoresis, impedance spectroscopy, colorimetric sensing, optical sensing and inertial sensing. The chapter provides a state-of-the-art review of basic techniques, sensing methodologies and applications for DNA-based diagnostics as carried out by industry.