BITS Faculty Publications

Permanent URI for this communityhttp://localhost:4000/handle/123456789/1867

Browse

Filters

20223

Settings

Author: search.filters.author.Jain, AnkitSubject: search.filters.subject.Hyaluronic acid liposomes

Search Results

Now showing 1 - 3 of 3
  • No Thumbnail Available
    Item
    Opportunities in combinational chemo-immunotherapy for breast cancer using nanotechnology: an emerging landscape
    (Taylor & Francis, 2022-02) Jain, Ankit
    Breast carcinoma (BC) is one of the most frequent causes of cancer-related death among women, which is due to the poor response to conventional therapy. There are several complications associated with monotherapy for cancer, such as cytotoxicity to normal cells, multidrug resistance (MDR), side effects, and limited applications. To overcome these challenges, a combination of chemotherapy and immunotherapy (monoclonal antibodies, anticancer vaccines, checkpoint inhibitors, and cytokines) has been introduced. Drug delivery systems (DDSs) based on nanotechnology have more applications in BC treatment owing to their controlled and targeted drug release with lower toxicity and reduced adverse drug effects. Several nanocarriers, such as liposomes, nanoparticles, dendrimers, and micelles, have been used for the effective delivery of drugs.
  • No Thumbnail Available
    Item
    Liposomal delivery system
    (Springer, 2022-03) Jain, Ankit
    Liposomes are biodegradable and biocompatible lipid bilayer vesicles that are employed as potential carriers for the delivery of drugs to the desired site. It is used for the delivery of both hydrophobic and hydrophilic drugs. Because of the variability in composition and structural properties, liposomes are widely used in biomedical applications. Recently, multifunctional liposomes have been reported for tumor targeting. Liposomal delivery systems are modified in several ways according to their applications. Ligand-modified liposomes are used for targeted drug delivery. Stimuli-sensitive liposomes are used to obtain the trigger drug release at the site of action. Theranostic liposomal systems are used for diagnosis as well as therapeutic purposes. This chapter highlights the basics and classification of liposomes. It encompasses a detailed account of ligand targeted liposomes (such as folate, transferrin, mannose, hyaluronic acid, and asialoglycoprotein), and stimuli-sensitive liposomes (such as pH, temperature, magnetic field, hypoxia, and photo-triggered) for tumor targeting. It also includes some marketed liposomal products used for cancer treatment
  • No Thumbnail Available
    Item
    Hyaluronic acid functionalized liposomes embedded in biodegradable beads for duo drugs delivery to oxaliplatin-resistant colon cancer
    (Elsevier, 2022-11) Jain, Ankit
    Oxaliplatin (OHP) resistance is a major hurdle in the chemotherapeutic treatment of colorectal cancer (CRC). The present study aimed to formulate Eudragit S-100 (ES-100) coated alginate beads bearing drugs loaded targeted liposomes for simultaneous delivery of OHP and curcumin (CUR) to exert a synergistic therapeutic effect on OHP- resistant HT-29 cell line