Antidepressant-like activity of (4-phenylpiperazin-1-yl) (quinoxalin-2-yl) methanone (4a), a novel 5-HT3 receptor antagonist: An investigation in behaviour-based rodent models of depression
| dc.contributor.author | Mahesh, R. | |
| dc.date.accessioned | 2023-11-21T05:03:41Z | |
| dc.date.available | 2023-11-21T05:03:41Z | |
| dc.date.issued | 2012-09 | |
| dc.description.abstract | The present study was designed to investigate the antidepressant potential of (4-phenylpiperazin-1-yl) (quinoxalin-3-yl) methanone (4a), a novel 5-HT3 receptor antagonist, with an optimal log P (2.84) and pA2 value (7.3) greater than ondansetron (6.9) using rodent behavioural models of depression. | en_US |
| dc.identifier.uri | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3480784/ | |
| dc.identifier.uri | http://dspace.bits-pilani.ac.in:8080/xmlui/handle/123456789/13200 | |
| dc.language.iso | en | en_US |
| dc.publisher | Wolters Kluwer | en_US |
| dc.subject | Pharmacy | en_US |
| dc.subject | (4-phenylpiperazin-1-yl) (quinoxalin-2-yl) methanone | en_US |
| dc.subject | 4a | en_US |
| dc.subject | 5-HT3 receptor antagonist | en_US |
| dc.subject | Depression | en_US |
| dc.subject | Forced swim test (FST) | en_US |
| dc.subject | Olfactory bulbectomy (OBX) | en_US |
| dc.title | Antidepressant-like activity of (4-phenylpiperazin-1-yl) (quinoxalin-2-yl) methanone (4a), a novel 5-HT3 receptor antagonist: An investigation in behaviour-based rodent models of depression | en_US |
| dc.type | Article | en_US |
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