Cyproheptadine, a SET7/9 inhibitor, reduces hyperglycaemia-induced ER stress alleviating inflammation and fibrosis in renal tubular epithelial cells
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Date
2022-08
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Publisher
Taylor & Francis
Abstract
Persistent hyperglycaemia increases SET7/9 expression and endoplasmic reticulum (ER) stress which causes inflammation, apoptosis, and fibrosis in renal tubular epithelial cells leading to diabetic kidney disease (DKD)
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Keywords
Pharmacy, Cyproheptadine, Fibrosis, Diabetic kidney disease (DKD)