Chloroquine induces transitory attenuation of proliferation of human lung cancer cells through regulation of mutant P53 and YAP

Abstract

Non-small cell lung carcinoma (NSCLC) is the most common cause of cancer-associated deaths worldwide. Though recent development in targeted therapy has improved NSCLC prognosis, yet there is an unmet need to identify novel causative factors and appropriate therapeutic regimen against NSCLCs.